Wuhan Fine Biotech Co., Ltd.'s GSDMD antibody is a Mouse monoclonal antibody. The GSDMD antibody was generated using Gasdermin D, and GSDMD as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunofluorescence, and Western Blot.
Description
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death